Gene polymorphisms in asthma: a narrative review.

ABSTRACT:

Background and objective

Asthma is a heterogeneous disease caused by interactions between genetic and environmental factors. Genome-wide association studies (GWAS) have revealed that genetic variation plays a crucial role in the occurrence and development of asthma. The objective is to systematically review the existing literature on the association between gene polymorphisms and asthma to better understand the relationship between genetic factors and the occurrence and development of asthma.

Methods

We used keywords "asthma" and "gene polymorphism" with their combinations to search for relevant literature published from 2000 to 2021 in the PubMed database and the foreign medical literature retrieval service (FMRS). All articles included in the review are English. Then, we s

SUBMITTER: Shi F 

PROVIDER: S-EPMC9279821 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature