Improved Functional Assessment of Ischemic Severity Using 3D Printed Models.

ABSTRACT:

Objective

To develop a novel in vitro method for evaluating coronary artery ischemia using a combination of non-invasive coronary CT angiograms (CCTA) and 3D printing (FFR_3D).

Methods

Twenty eight patients with varying degrees of coronary artery disease who underwent non-invasive CCTA scans and invasive fractional flow reserve (FFR) of their epicardial coronary arteries were included in this study. Coronary arteries were segmented and reconstructed from CCTA scans using Mimics (Materialize). The segmented models were then 3D printed using a Carbon M1 3D printer with urethane methacrylate (UMA) family of rigid resins. Physiological coronary circulation was modeled in vitro as flow-dependent stenosis resistance in series with variable downstream resist

SUBMITTER: Kolli KK 

PROVIDER: S-EPMC9279862 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature