Analysis of current status of quantitative detection of biomarkers for liver fibrosis in Clinical labs in China.

ABSTRACT:

Aim

To explore the quality control and implementation of the quantitative detection of liver fibrosis biomarkers, laminin (LN), collagen IV (Col Ⅳ), procollagen III amino-terminal propeptide (PⅢNP), hyaluronic acid (HA), and cholyglycine (CG), in China.

Methods

Two quality control products were measured in different laboratories using different measurement methods and reagents, and the acquired results were subjected to analysis. The quantitative detection technique was based on the conventional assessment criteria, with a target value ±30% being employed.

Results

Hundred labs were involved in the External Quality Assessment with 88 laboratories completing the assessment, and the pass rates were 84%, 80.2%, 67.5%, 77.3%, and 58.3% for HA, LN, PⅢNP, Col Ⅳ, and CG, resp

SUBMITTER: Zhang C 

PROVIDER: S-EPMC9279982 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature