Long-term Immune Response to SARS-CoV-2 Infection Among Children and Adults After Mild Infection.

ABSTRACT:

Importance

Understanding the long-term immune response against SARS-CoV-2 infection in children is crucial to optimize vaccination strategies. Although it is known that SARS-CoV-2 antibodies may persist in adults 12 months after infection, data are limited in the pediatric population.

Objective

To examine long-term anti-SARS-CoV-2 spike receptor-binding domain (S-RBD) IgG kinetics in children after SARS-CoV-2 infection.

Design, setting, and participants

In this single-center, prospective cohort study, patients were enrolled consecutively from April 1, 2020, to August 31, 2021, at the COVID-19 Family Cluster Follow-up Clinic, Department of Women's and Children's Health, University Hospital of Padua. A cohort of 252 COVID-19 family clusters underwent serologic follow-up

SUBMITTER: Di Chiara C 

PROVIDER: S-EPMC9280400 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature