Identification of RPL5 gene variants and the risk of hepatic vein thrombosis in Saudi patients.

ABSTRACT:

Objectives

To identify ribosome protein L5 gene variants and the risk of hepatic vein thrombosis in Saudi patients.

Methods

A case-control study was conducted during the period of May 2018 to September 2019. Sixty-five patient cases of hepatic vein thrombosis (HVT) were chosen, and 50 healthy individuals of the same ages and both gender were set as a control group. The genotype of the gene RPL5 was determined by PCR please provide abbreviation in full and capillary electrophoresis. Sanger sequencing for genetically screened variants was applied for the RPL5 gene.

Results

Alleles A at variant rs182018447 and T allele at variant rs559377519 were strongly corelated (p=0.009 and p=0.037, respectively) with the risk of HVT. The genotype frequencies of

SUBMITTER: Hassan FM 

PROVIDER: S-EPMC9280514 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature