Ontology highlight
ABSTRACT:
SUBMITTER: Al Nahas K
PROVIDER: S-EPMC9280716 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Al Nahas Kareem K Fletcher Marcus M Hammond Katharine K Nehls Christian C Cama Jehangir J Ryadnov Maxim G MG Keyser Ulrich F UF
Analytical chemistry 20220627 27
Host defense or antimicrobial peptides hold promise for providing new pipelines of effective antimicrobial agents. Their activity quantified against model phospholipid membranes is fundamental to a detailed understanding of their structure-activity relationships. However, classical characterization assays often lack the ability to achieve this insight. Leveraging a highly parallelized microfluidic platform for trapping and studying thousands of giant unilamellar vesicles, we conducted quantitati ...[more]