A Potent Antioxidant Sesquiterpene, Abelsaginol, from Abelmoschus sagittifolius: Experimental and Theoretical Insights.

ABSTRACT: The sesquiterpenoid compound abelsaginol (AS) was successfully isolated from Abelmoschus sagittifolius for the first time. The compound was identified using NMR and MS data. The antioxidant activity of AS was also evaluated both theoretically and experimentally. AS was found to be a weak HOO^• radical scavenger in organic solvents such as pentyl ethanoate and dimethyl sulfoxide (k _overall = ∼ 10² M^-1 s^-1), in a good agreement with the results of the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) assay. However, AS exhibited good HOO^• antiradical activity in water at pH 7.40 (k _overall = 9.00 × 10⁶ M^-1 s^-1) through the single-e

SUBMITTER: Ngoc TD 

PROVIDER: S-EPMC9280938 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature