Synthesis, structural characterization, and evaluation of new peptidomimetic Schiff bases as potential antithrombotic agents
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ABSTRACT: New Schiff bases functionalized with amide and phenolic groups synthesized by the condensation of 2-hydroxybenzaldehyde and 2-hydroxyacetophenone with amino acid amides which in turn were prepared in two steps from N-Boc-amino acids and homoveraltrylamine through intermediate compounds N-Boc-amino acids amides. The compounds were characterized by elemental analysis, FT-IR, UV–Vis, and NMR spectroscopy. The crystal structures of three Schiff bases were determined by single crystal X-ray diffraction. There exists O–H Graphical abstract
Supplementary Information
The online version contains supplementary material available at 10.1007/s00706-022-02936-6.
SUBMITTER: Eranna S
PROVIDER: S-EPMC9281246 | biostudies-literature |
REPOSITORIES: biostudies-literature
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