Application of Dynamic ¹⁸F-FDG PET/CT for Distinguishing Intrapulmonary Metastases from Synchronous Multiple Primary Lung Cancer.

ABSTRACT: It has been a big challenge to distinguish synchronous multiple primary lung cancer (sMPLC) from primary lung cancer with intrapulmonary metastases (IPM). We aimed to assess the clinical application of dynamic ¹⁸F-FDG PET/CT in patients with multiple lung cancer nodules. We enrolled patients with multiple pulmonary nodules who had undergone dynamic ¹⁸F-FDG PET/CT and divided them into sMPLC and IPM groups based on comprehensive features. The SUV_max, fitted K _i value based on dynamic scanning, and corresponding maximum diameter (D _max) from the two largest tumors were determined in each patient. We determined the absolute between-tumor difference of SUV_max/D _max and K _i

SUBMITTER: Lv W 

PROVIDER: S-EPMC9281433 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature