A Ring Expansion Approach To N-oxy-2,5-diketopiperazines.

ABSTRACT: A ring expansion of tetramic acids (pyrrolidine-2,4-diones) to N-oxy-2,5-diketopiperazines (DKPs) is described. This method allows for the facile and late-stage construction of the hydroxamic acid moiety and can thereby serve as a general method for accessing N-oxy-2,5-DKP natural products.

SUBMITTER: Jackson AC 

PROVIDER: S-EPMC9281442 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature