Mitochondrial Homeostasis in Obesity-related Hypertriglyceridemia.

ABSTRACT:

Context

The prevalence of obesity and hypertriglyceridemia is an alarming worldwide health issue. Mitochondria play a central role in these disorders as they control cell metabolism.

Objective

The aim of the present study was to characterize mitochondrial homeostasis in subcutaneous and visceral adipose tissue (SAT and VAT) in grade III obese patients with and without hypertriglyceridemia. Moreover, this study presents the evaluation of mitochondrial fitness as a marker for hypertriglyceridemia improvement.

Patients

Eight control and 12 hypertriglyceridemic (HTG) grade III obese subjects undergoing bariatric surgery were included.

Main outcome measures

Anthropometric and biochemical data were obtained before and 3 months after surgery. Mitochondrial homeostasis

SUBMITTER: Mela V 

PROVIDER: S-EPMC9282366 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature