Association between IgG antibody levels and adverse events after first and second Bnt162b2 mRNA vaccine doses.

ABSTRACT:

Objectives

This study sought to correlate the SARS-CoV-2 IgG antibody response level to the BNT162b2 (Pfizer BioNTech) mRNA vaccine after the first and second doses with the reported adverse events.

Methods

This cohort study examined the adverse events profiles of people vaccinated with BNT162b2 in our institute between late 2020 and May 2021. Adverse events, age, and sex were reported using an electronic questionnaire, and their SARS-CoV-2 IgG antibody levels were retrieved from the hospital database.

Results

Between 20 December 2020 and 31 May 2021, the adverse events questionnaire was completed by 9700 individuals who received the first vaccine dose and 8321 who received the second dose. After the first and second doses, the average antibody levels were 62.34 AU/mL

SUBMITTER: Braun E 

PROVIDER: S-EPMC9283125 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature