Postoperative fluid balance and outcomes after Pancreaticoduodenectomy: a retrospective study in 301 patients.

ABSTRACT:

Background

The incidence of postoperative morbidity after pancreaticoduodenectomy (PD) is high; however, whether fluid management after surgery affects postoperative morbidity is unclear. This study aimed to determine whether fluid balance in patients undergoing PD is associated with postoperative complications and mortality.

Methods

Data from a computer-based database of patients who underwent PD between 2016 and 2019 were retrospectively analyzed. Patients were stratified into four quartiles according to their fluid balance at 0-24, 24-48, 48-72, and 72-96 h after surgery. The predefined primary outcome measures were morbidity and mortality rates.

Results

A total of 301 patients were included. The morbidity and mortality rates in the cohort were 56.5% and 3.7%, resp

SUBMITTER: Zhang H 

PROVIDER: S-EPMC9283355 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature