Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage: Relation to Neurointensive Care Targets.

ABSTRACT:

Background

The primary aim was to determine to what extent continuously monitored neurointensive care unit (neuro-ICU) targets predict cerebral blood flow (CBF) and delivery of oxygen (CDO₂) after aneurysmal subarachnoid hemorrhage. The secondary aim was to determine whether CBF and CDO₂ were associated with clinical outcome.

Methods

In this observational study, patients with aneurysmal subarachnoid hemorrhage treated at the neuro-ICU in Uppsala, Sweden, from 2012 to 2020 with at least one xenon-enhanced computed tomography (Xe-CT) obtained within the first 14 days post ictus were included. CBF was measured with the Xe-CT and CDO₂ was calculated based on CBF and arterial oxygen content. Regional cerebral hypoperfusion was defined as CBF < 20 

SUBMITTER: Svedung Wettervik T 

PROVIDER: S-EPMC9283361 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature