Tissue volume estimation and age prediction using rapid structural brain scans.

ABSTRACT: The multicontrast EPImix sequence generates six contrasts, including a T₁-weighted scan, in ~1 min. EPImix shows comparable diagnostic performance to conventional scans under qualitative clinical evaluation, and similarities in simple quantitative measures including contrast intensity. However, EPImix scans have not yet been compared to standard MRI scans using established quantitative measures. In this study, we compared conventional and EPImix-derived T₁-weighted scans of 64 healthy participants using tissue volume estimates and predicted brain-age. All scans were pre-processed using the SPM12 DARTEL pipeline, generating measures of grey matter, white matter and cerebrospinal fluid volume. Brain-age was predicted using brainageR, a Gaussian Processes Regression mode

SUBMITTER: Hobday H 

PROVIDER: S-EPMC9283414 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature