Investigation on Potential ESKAPE Surrogates for 222 and 254 nm Irradiation Experiments.

ABSTRACT:

Background

Due to the increase in multidrug-resistant pathogens, it is important to investigate further antimicrobial options. In order not to have to work directly with pathogens, the investigation of possible surrogates is an important aspect. It is examined how suitable possible surrogate candidates for ESKAPE pathogens are for UVC applications. In addition, the inactivation sensitivities to 222 and 254 nm radiation are compared in relation.

Methods

Non-pathogenic members (Enterococcus mundtii, Staphylococcus carnosus, Acinetobacter kookii, Pseudomonas fluorescens and Escherichia coli) of genera of ESKAPE strains were photoinactivated in PBS with irradiation wavelengths of 222 and 254 nm (no non-pathogenic Klebsiella was available). Log reduction dose

SUBMITTER: Gierke AM 

PROVIDER: S-EPMC9284107 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature