Lung transplantation disparities based on diagnosis for patients bridging to transplant on extracorporeal membrane oxygenation.

ABSTRACT:

Background

Extracorporeal membrane oxygenation (ECMO) is increasingly utilized as a bridge to lung transplantation, but ECMO status is not explicitly accounted for in the Lung Allocation Score (LAS). We hypothesized that among waitlist patients on ECMO, patients with pulmonary arterial hypertension (PAH) would have lower transplantation rates.

Methods

Using United Network for Organ Sharing data, we conducted a retrospective cohort study of patients who were ≥12 years old, active on the lung transplant waitlist, and required ECMO support from June 1, 2015 through June 12, 2020. Multivariable competing risk analysis was used to examine waitlist outcomes.

Results

1064 waitlist subjects required ECMO support; 40 (3.8%) had obstructive lung disease (OLD), 97 (9.1%) had PAH

SUBMITTER: Furfaro D 

PROVIDER: S-EPMC9284417 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature