Multicomponent Copolymer Planar Membranes with Nanoscale Domain Separation.

ABSTRACT: Domain separation is crucial for proper cellular function and numerous biomedical technologies, especially artificial cells. While phase separation in hybrid membranes containing lipids and copolymers is well-known, the membranes' overall stability, limited by the lipid part, is hindering the technological applications. Here, we introduce a fully synthetic planar membrane undergoing phase separation into domains embedded within a continuous phase. The mono- and bilayer membranes are composed of two amphiphilic diblock copolymers (PEO₄₅-b-PEHOx₂₀ and PMOXA₁₀-b-PDMS₂₅) with distinct properties and mixed at various concentrations. The molar ratio of the copolymers in the mixture and the nature of the solid support were the key paramete

SUBMITTER: Bina M 

PROVIDER: S-EPMC9284607 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature