Associations between glycated hemoglobin and the risks of incident cardiovascular diseases in patients with gout.

ABSTRACT:

Background

Evidence for the relationship between glycated hemoglobin (HbA1c) levels and risk of cardiovascular diseases (CVD) in patients with gout remained sparse and limited. This study aims to explore the associations between HbA1c levels and risks of incident CVD in patients with gout.

Methods

We included patients with gout who had an HbA1c measurement at baseline from the UK Biobank. CVD events were identified from through medical and death records. We used multivariable Cox proportional hazards model with a restricted cubic spline to assess the potential non-linear effect of HbA1c on CVD risk.

Results

We included a total of 6,685 patients (mean age 59.7; 8.1% females) with gout for analyses. During a mean follow-up of 7.3 years, there were 1,095 CVD events docum

SUBMITTER: Li L 

PROVIDER: S-EPMC9284835 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature