Foetal tobacco and cannabis exposure, body fat and cardio-metabolic health in childhood.

ABSTRACT:

Background

Foetal tobacco and cannabis exposure may have persistent cardio-metabolic consequences in the offspring.

Objective

We examined the associations of maternal and paternal tobacco and cannabis use during pregnancy with offspring body fat and cardio-metabolic outcomes.

Methods

In a population-based prospective cohort study among 4792 mothers, fathers, and children, we assessed parental substance use by questionnaires. Childhood outcomes included body mass index (BMI), body fat, blood pressure, and lipid, glucose and insulin concentrations at 10 years.

Results

Children exposed to maternal tobacco use during pregnancy had a higher android/gynoid fat mass ratio (difference 0.22 SDS, 95% confidence interval [CI]: 0.13, 0.30), fat mass index (difference 0.20

SUBMITTER: Cajachagua-Torres KN 

PROVIDER: S-EPMC9285056 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature