Collision cross-section analysis of self-assembled metallomacrocycle isomers and isobars via ion mobility mass spectrometry.

ABSTRACT:

Rationale

Coordinatively driven self-assembly of transition metal ions and bidentate ligands gives rise to organometallic complexes that usually contain superimposed isobars, isomers, and conformers. In this study, the double dispersion ability of ion mobility mass spectrometry (IM-MS) was used to provide a comprehensive structural characterization of the self-assembled supramolecular complexes by their mass and charge, revealed by the MS event, and their shape and collision cross-section (Ω), revealed by the IM event.

Methods

Self-assembled complexes were synthesized by reacting a bis(terpyridine) ligand exhibiting a 60^o dihedral angle between the two ligating terpyridine sites (T) with divalent Zn, Ni, Cd, or Fe. The products were isolated as (Metal²⁺

SUBMITTER: Endres KJ 

PROVIDER: S-EPMC9285404 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature