Ventricular wall stress and wall shear stress homeostasis predicts cardiac remodeling during pregnancy: A modeling study.

ABSTRACT: Pregnancy is a unique and dynamic process characterized by significant changes in the maternal cardiovascular system that are required to satisfy the increased maternal and fetal metabolic demands. Profound structural and hemodynamic adaptations occur during healthy pregnancy that allows the mother to maintain healthy hemodynamics and provide an adequate uteroplacental blood circulation to ensure physiological fetal development. Investigating these adaptations is crucial for understanding the physiology of pregnancy and may provide important insights for the management of high-risk pregnancies. However, no previous modeling studies have investigated the maternal cardiac structural changes that occur during gestation. This study, therefore, had two aims. The first was to develop a lumped pa

SUBMITTER: Comunale G 

PROVIDER: S-EPMC9285413 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature