3D Printed Bioinspired Stents with Photothermal Effects for Malignant Colorectal Obstruction.

ABSTRACT: Stent placement is an effective palliation therapy for malignant colorectal obstruction. However, recurrent obstruction is a common severe complication caused by tumor ingrowth into the stent lumen. Conventional covered stents play a part in preventing the tumor from growing inward but at the expense of significantly increasing the risk of stent migration. Therefore, there is an urgent demand to develop stents with sustained antitumor and antimigration abilities. Herein, we propose a facile method for fabricating multifunctional bioinspired colorectal stents using 3D printing technology. Inspired by high-adhesion biological structures (gecko feet, tree frog toe pads, and octopus suckers) in nature, different types of bioinspired colorectal stents are designed to reduce migration. After fun

SUBMITTER: Lin C 

PROVIDER: S-EPMC9285633 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature