The inability to belch syndrome: A study using concurrent high-resolution manometry and impedance monitoring.

ABSTRACT:

Introduction

Although inability to belch has previously been linked to dysfunction of the upper esophageal sphincter (UES), its underlying pathogenesis remains unclear. Our aim was to study mechanisms underlying inability to belch and the effect of UES botulinum toxin (botox) injections in these patients.

Methods

We prospectively enrolled consecutive patients with symptoms of inability to belch. Patients underwent stationary high-resolution impedance manometry (HRIM) with belch provocation and ambulatory 24-h pH-impedance monitoring before and 3 months after UES botox injection.

Results

Eight patients (four males, age 18-37 years) were included. Complete and normal UES relaxation occurred in response to deglutition in all patients. A median number of 33(15-64) gastroe

SUBMITTER: Oude Nijhuis RAB 

PROVIDER: S-EPMC9285907 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature