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Reducing pain in children with cancer: Methodology for the development of a clinical practice guideline.


ABSTRACT: Although pain is one of the most prevalent and bothersome symptoms children with cancer experience, evidence-based guidance regarding assessment and management is lacking. With 44 international, multidisciplinary healthcare professionals and nine patient representatives, we aimed to develop a clinical practice guideline (following GRADE methodology), addressing assessment and pharmacological, psychological, and physical management of tumor-, treatment-, and procedure-related pain in children with cancer. In this paper, we present our thorough methodology for this development, including the challenges we faced and how we approached these. This lays the foundation for our clinical practice guideline, for which there is a high clinical demand.

SUBMITTER: Loeffen EAH 

PROVIDER: S-EPMC9286396 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Reducing pain in children with cancer: Methodology for the development of a clinical practice guideline.

Loeffen Erik A H EAH   Kremer Leontien C M LCM   van de Wetering Marianne D MD   Mulder Renée L RL   Font-Gonzalez Anna A   Dupuis Lee L LL   Campbell Fiona F   Tissing Wim J E WJE  

Pediatric blood & cancer 20190307 6


Although pain is one of the most prevalent and bothersome symptoms children with cancer experience, evidence-based guidance regarding assessment and management is lacking. With 44 international, multidisciplinary healthcare professionals and nine patient representatives, we aimed to develop a clinical practice guideline (following GRADE methodology), addressing assessment and pharmacological, psychological, and physical management of tumor-, treatment-, and procedure-related pain in children wit  ...[more]

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