Influence of placebo effect in mental disorders research: A systematic review and meta-analysis.

ABSTRACT:

Background

Randomized controlled trials (RCT) in mental disorders research commonly use active control groups including psychotherapeutic shams or inactive medication. This meta-analysis assessed whether placebo conditions (active controls) had an effect compared to no treatment or usual care (passive controls).

Methods

PubMed, Scopus, PsycINFO, PsycARTICLES, Ovid, the Cochrane Central Register of Controlled Trials and Web of Science were searched from inception to April 2021 and reference lists of relevant articles. Three-arm RCTs, including active and passive control groups, were selected. Where individual standardized mean difference (SMD) was calculable, random effects meta-analyses were performed to estimate an overall effect size with 95% confidence intervals (CI) comp

SUBMITTER: Fernandez-Lopez R 

PROVIDER: S-EPMC9286474 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature