Designing broadband pulsed dynamic nuclear polarization sequences in static solids.

ABSTRACT: Dynamic nuclear polarization (DNP) is a nuclear magnetic resonance (NMR) hyperpolarization technique that mediates polarization transfer from unpaired electrons with large thermal polarization to NMR-active nuclei via microwave (mw) irradiation. The ability to generate arbitrarily shaped mw pulses using arbitrary waveform generators allows for remarkable improvement of the robustness and versatility of DNP. We present here novel design principles based on single-spin vector effective Hamiltonian theory to develop new broadband DNP pulse sequences, namely, an adiabatic version of XiX (X-inverse X)-DNP and a broadband excitation by amplitude modulation (BEAM)-DNP experiment. We demonstrate that the adiabatic BEAM-DNP pulse sequence may achieve a ¹H enhancement factor of ∼360, whic

SUBMITTER: Wili N 

PROVIDER: S-EPMC9286509 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature