Emerging paradigm shift toward proactive topical treatment of psoriasis: A narrative review.

ABSTRACT: Psoriasis (PsO) requires safe and effective long-term management to reduce the risk of recurrence and decrease the frequency of relapse. Topical PsO therapies are a cornerstone in the management of PsO though safety concerns limit the chronic, continuous use of topical corticosteroids and/or vitamin D₃ analogs. Evidence-based guidelines on optimal treatment targets and maintenance therapy regimens are currently lacking. This review explores the evidence supporting approaches to maintenance topical therapy for PsO including continuous long-term therapy, chronic intermittent use, step-down therapy, sequential or pulse therapy regimens, and proactive maintenance therapy. Several unaddressed questions are discussed including how and when to transition from acute to maintenance thera

SUBMITTER: Papp KA 

PROVIDER: S-EPMC9286633 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature