Prediction Models for Osteoporotic Fractures Risk: A Systematic Review and Critical Appraisal.

ABSTRACT: Osteoporotic fractures (OF) are a global public health problem currently. Many risk prediction models for OF have been developed, but their performance and methodological quality are unclear. We conducted this systematic review to summarize and critically appraise the OF risk prediction models. Three databases were searched until April 2021. Studies developing or validating multivariable models for OF risk prediction were considered eligible. Used the prediction model risk of bias assessment tool to appraise the risk of bias and applicability of included models. All results were narratively summarized and described. A total of 68 studies describing 70 newly developed prediction models and 138 external validations were included. Most models were explicitly developed (n=31, 44%) and validate

SUBMITTER: Sun X 

PROVIDER: S-EPMC9286920 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature