Impact of renal impairment on atrial fibrillation: ESC-EHRA EORP-AF Long-Term General Registry.

ABSTRACT:

Background

Atrial fibrillation (AF) and renal impairment share a bidirectional relationship with important pathophysiological interactions. We evaluated the impact of renal impairment in a contemporary cohort of patients with AF.

Methods

We utilised the ESC-EHRA EORP-AF Long-Term General Registry. Outcomes were analysed according to renal function by CKD-EPI equation. The primary endpoint was a composite of thromboembolism, major bleeding, acute coronary syndrome and all-cause death. Secondary endpoints were each of these separately including ischaemic stroke, haemorrhagic event, intracranial haemorrhage, cardiovascular death and hospital admission.

Results

A total of 9306 patients were included. The distribution of patients with no, mild, moderate and severe renal im

SUBMITTER: Ding WY 

PROVIDER: S-EPMC9287022 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature