Reliability and validity of the Roche PD Mobile Application for remote monitoring of early Parkinson's disease.

ABSTRACT: Digital health technologies enable remote and therefore frequent measurement of motor signs, potentially providing reliable and valid estimates of motor sign severity and progression in Parkinson's disease (PD). The Roche PD Mobile Application v2 was developed to measure bradykinesia, bradyphrenia and speech, tremor, gait and balance. It comprises 10 smartphone active tests (with ½ tests administered daily), as well as daily passive monitoring via a smartphone and smartwatch. It was studied in 316 early-stage PD participants who performed daily active tests at home then carried a smartphone and wore a smartwatch throughout the day for passive monitoring (study NCT03100149). Here, we report baseline data. Adherence was excellent (96.29%). All pre-specified sensor features exhibited good-to-

SUBMITTER: Lipsmeier F 

PROVIDER: S-EPMC9287320 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature