Age-related changes of whole-brain dynamics in spontaneous neuronal coactivations.

ABSTRACT: Human brains experience whole-brain anatomic and functional changes throughout the lifespan. Age-related whole-brain network changes have been studied with functional magnetic resonance imaging (fMRI) to determine their low-frequency spatial and temporal characteristics. However, little is known about age-related changes in whole-brain fast dynamics at the scale of neuronal events. The present study investigated age-related whole-brain dynamics in resting-state electroencephalography (EEG) signals from 73 healthy participants from 6 to 65 years old via characterizing transient neuronal coactivations at a resolution of tens of milliseconds. These uncovered transient patterns suggest fluctuating brain states at different energy levels of global activations. Our results indicate that with inc

SUBMITTER: Shou G 

PROVIDER: S-EPMC9287374 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature