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The role of latitude and infections in the month-of-birth effect linked to schizophrenia.


ABSTRACT: There is an intriguing association between winter births and subsequent increased risk of schizophrenia. However, little is known about the environmental risk factors that contribute this month-of-birth effect. The aims of this study were to carry out a systematic review and meta-analysis of studies investigating the month-of-birth effect in schizophrenia and to explore possible factors such as latitude, daylight and infections that could explain this epidemiological observation. Medline, Embase and the Cochrane Library were searched for articles published up to December 23, 2021. Study selection, data extraction and analysis were undertaken according to Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines. Generic inverse-variance with random effects models were used

SUBMITTER: Saatci D 

PROVIDER: S-EPMC9287767 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature