Glycemic control in critically ill patients with or without diabetes

ABSTRACT:

Background

Early randomized controlled trials have demonstrated the benefits of tight glucose control. Subsequent NICE-SUGAR study found that tight glucose control increased mortality. The optimal glucose target in diabetic and nondiabetic patients remains unclear. This study aimed to evaluate the relationship between blood glucose levels and outcomes in critically ill patients with or without diabetes.

Methods

This was a retrospective analysis of the eICU database. Repeat ICU stays, ICU stays of less than 2 days, patients transferred from other ICUs, those with less than 2 blood glucose measurements, and those with missing data on hospital mortality were excluded. The primary outcome was hospital mortality. Generalised additive models were used to model relationship betw

SUBMITTER: Fong K 

PROVIDER: S-EPMC9288031 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature