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MiRNA expression in COVID-19.

ABSTRACT: Coronavirus disease 2019 (COVID-19) is regarded as a challenge in health system. Several studies have assessed the immune-related aspect of this disorder to identify the host-related factors that affect the course of COVID-19. microRNAs (miRNAs) as potent regulators of immune responses have gained much attention in this regard. Recent studies have shown aberrant expression of miRNAs in COVID-19 in association with disease course. Differentially expressed miRNAs have been enriched in pathways related with inflammation and antiviral immune response. miRNAs have also been regarded as potential therapeutic targets in COVID-19, particularly for management of pathological consequences of COVID-19. In the current review, we summarize the data about dysregulation of miRNAs in COVID-19.

SUBMITTER: Roustai Geraylow K

PROVIDER: S-EPMC9288248 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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miRNA expression in COVID-19.

Roustai Geraylow Kiarash K Hemmati Romina R Kadkhoda Sepideh S Ghafouri-Fard Soudeh S

Gene reports 20220716

Coronavirus disease 2019 (COVID-19) is regarded as a challenge in health system. Several studies have assessed the immune-related aspect of this disorder to identify the host-related factors that affect the course of COVID-19. microRNAs (miRNAs) as potent regulators of immune responses have gained much attention in this regard. Recent studies have shown aberrant expression of miRNAs in COVID-19 in association with disease course. Differentially expressed miRNAs have been enriched in pathways rel ...[more]

PMID: 35875722

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