Biosynthetic studies through feeding experiments in Eclipta prostrata (L.) L. hairy roots.

ABSTRACT: Eclipta prostrata (L.) L. is a medicinal plant of the Asteraceae family, and several extracts and isolated compounds of E. prostrata (L.) L. showed a wide range of biological activities such as antimicrobial, anticancer, hepatoprotective, neuroprotective, hair growth promoting activities, and more recently against covid-19. Eclipta prostrata (L.) L. hairy roots produce wedelolactone (WL), demethylwedelolactone (DWL) and 3,5-di-O-caffeoylquinic acid (3,5-diCQA), and there is no data in literature regarding biosynthetic pathways are involved. To verify the biosynthetic route, feeding experiments were carried out using sodium [2-¹³C]acetate, [3-¹³C]dl-phenylalanine, and ¹³C-labeled compounds (WL, DWL and 3,5-diCQA) were detected by

SUBMITTER: Lopes AA 

PROVIDER: S-EPMC9288585 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature