Association between central haemodynamics and renal function in advanced heart failure: a nationwide study from Sweden.

ABSTRACT:

Aims

Renal dysfunction in patients with heart failure (HF) has traditionally been attributed to declining cardiac output and renal hypoperfusion. However, other central haemodynamic aberrations may contribute to impaired kidney function. This study assessed the relationship between invasive central haemodynamic measurements from right-heart catheterizations and measured glomerular filtration rate (mGFR) in advanced HF.

Methods and results

All patients referred for heart transplantation work-up in Sweden between 1988 and 2019 were identified through the Scandiatransplant organ-exchange organization database. Invasive haemodynamic variables and mGFR were retrieved retrospectively. A total of 1001 subjects (49 ± 13 years; 24% female) were eligible for the study. Analysis of cov

SUBMITTER: Bobbio E 

PROVIDER: S-EPMC9288757 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature