Ivabradine in heart failure patients with reduced ejection fraction and history of paroxysmal atrial fibrillation.

ABSTRACT:

Aims

Ivabradine is indicated for heart failure (HF) patients with reduced ejection fraction (HFrEF), but limited data are available with regards to the use of ivabradine in those with a history of paroxysmal atrial fibrillation (AF). To assess the effect of ivabradine in HFrEF patients with paroxysmal AF, we analysed heart failure (HF) hospitalization and mortality from multiple-centre registry database.

Methods and results

We conducted a multicentre observational matched cohort study, and this study enrolled patient with symptomatic HFrEF from 1 January 2015 to 31 December 2018 who had a history of paroxysmal AF in Chang Gung Memorial Hospital medical database in Taiwan. A total of 2042 patients were eligible for the study, of whom 887 were prescribed with ivabradine and 11

SUBMITTER: Lin YS 

PROVIDER: S-EPMC9288788 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature