Low mechano-energetic efficiency is associated with future left ventricular systolic dysfunction in hypertensives.

ABSTRACT:

Aims

In a hypertensive population with optimal blood pressure control with a long-term follow-up, we aimed at analysing possible predictors of left ventricular (LV) ejection fraction (LVEF) reduction, including indexed mechano-energetic efficiency (MEEi), a well-recognized echo-derived parameter of LV performance.

Methods and results

The study population included 5673 hypertensive patients from the Campania Salute Network with a long-term follow-up, normal baseline LVEF (≥50%), and no prevalent cardiovascular (CV) disease. Patients developing LVEF impairment (LVEF < 50% or a reduction of at least 10 percentage points compared with baseline) were compared with patients with persistently normal LVEF. Optimal blood pressure control was achieved in about 80% of patients. Patient

SUBMITTER: Manzi MV 

PROVIDER: S-EPMC9288798 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature