Giant cyst-like cortical tubers in an adult with tuberous sclerosis presenting as spastic tetraplegia

ABSTRACT:

Introduction and importance

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by inactivating mutations in TSC1 or TSC2 genes, resulting in benign lesions that involve multiple organs including the central nerves system.

Case presentation

A 39-year-old male of known TSC presented with inability to walk for two months. On physical examination, he was consciously oriented and cooperative, but he had spastic tetraparesis in the muscle-motor examination. On brain imaging, cystic lesions of various sizes in the supra and infratentorial regions were observed, consistent with giant cyst-like tubers. However, they could not differentiate from TSC related brain tumors based on the imaging findings. He underwent surgical intervention to resect/evacuate the l

SUBMITTER: Esmat H 

PROVIDER: S-EPMC9289415 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature