The Impact of Low-Level Viraemia on Virological Failure-Results From a Multicenter HIV Antiretroviral Therapy Cohort Study in Yunnan, China.

ABSTRACT:

Background

HIV viral load (VL) is an important indicator to monitor treatment response in antiretroviral therapy (ART). Patients on ART may experience viral blips, with low-level elevations of VL between 50 and 999 copies/mL known as low-level viraemia (LLV), but not reaching the threshold for virological failure (≥1,000 copies/mL) defined by WHO guidelines. The objective was to investigate the long-term impact of LLV on virological failure.

Methods

We analyzed adults who were ART naïve at baseline. LLV was defined as having an VL of 51-999 copies/mL at least once. The subjects with LLV were grouped into three categories: 51-199, 200-399, and 400-999 copies/mL. Patients with multiple episodes of LLV were classified based on the highest VL result. The subjects with LLV were a

SUBMITTER: An J 

PROVIDER: S-EPMC9289465 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature