Efficacy of selected Nigerian tropical plants in the treatment of COVID-19: in silico and in vitro investigations.

ABSTRACT: The whole world is still challenged with COVID-19 pandemic caused by Coronavirus-2 (SARS-CoV-2) which has affected millions of individuals around the globe. Although there are prophylactic vaccines being used, till now, there is ongoing research into discovery of drug candidates for total eradication of all types of coronaviruses. In this context, this study sought to investigate the inhibitory effects of six selected tropical plants against four pathogenic proteins of Coronavirus-2. The medicinal plants used in this study were selected based on their traditional applications in herbal medicine to treat COVID-19 and related symptoms. The biological activities (antioxidant, free radical scavenging, and anti-inflammatory activities) of the extracts of the plants were assessed using different

SUBMITTER: Oladele JO 

PROVIDER: S-EPMC9289936 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature