Determining Factors Influencing RAS Inhibitors Re-Initiation in ICU: A Modified Delphi Method.

ABSTRACT:

Background

Renin-angiotensin system inhibitors (RASi) are not re-initiated for almost a quarter of patients who suffered acute kidney injury 6 months after discharge. This discontinuation might be partly explained by the nephrotoxicity of these medications, yet they remain of benefit, especially for patients with heart failure.

Objective

To determine the factors deemed by clinicians to influence RASi re-initiation and set threshold values for important safety parameters.

Design

Three-round modified online Delphi survey.

Setting

The study was conducted in Quebec, Canada.

Participants

Twenty clinicians from nephrology, intensive care medicine, and internal medicine.

Measurements

The factors' importance was rated on 4-point Likert-type scale, ranging

SUBMITTER: Dahel H 

PROVIDER: S-EPMC9290153 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature