Systematic review and meta-analysis on the impact of the levonorgestrel-releasing intrauterine system in reducing risk of ovarian cancer.

ABSTRACT:

Background

Ovarian carcinoma (OC) is one of the most widespread tumors in the world and is characterized by low survival rates.

Objective

To determine whether the levonorgestrel-releasing intrauterine system (LNG-IUS) can prevent OC.

Search strategy

The literature until December 2020 were systematically reviewed according to the PRISMA Statement for Reporting Systematic Reviews (PROSPERO: CRD42019137957).

Selection criteria

Studies assessing the impact of LNG-IUS on the risk of OC were included.

Data collection and analysis

Data were extracted independently by two authors to ensure accuracy and consistency.

Main results

A total of 34 323 records were obtained, of which three satisfied the inclusion criteria. In total, 1687 events of OC in a popula

SUBMITTER: D'Alessandro G 

PROVIDER: S-EPMC9290617 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature