Immersion vaccines against Yersinia ruckeri infection in rainbow trout: Comparative effects of strain differences.

ABSTRACT: The protective effects of autogenous and commercial ERM immersion vaccines (bacterins based on Yersinia ruckeri, serotype O1, biotypes 1 and 2) for rainbow trout (Oncorhynchus mykiss) were compared in order to evaluate whether the use of local pathogen strains for immunization can improve protection. In addition, the effect of the bacterin concentration was established for the commercial product. Following sublethal challenge of vaccinated and non-vaccinated control fish with live bacteria, we followed the bacterial count in the fish (gills, liver and spleen). The expression of genes encoding immune factors (IL-1β, IL-6, IL-8, IL-10, IFN-γ, MHCI, MHCII, CD4, CD8, TCRβ, IgM, IgT, IgD, cathelicidins 1 and 2, SAA and C3) and densities of immune cells in organs were recorded. Both vaccines con

SUBMITTER: Yang H 

PROVIDER: S-EPMC9290694 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature