Assessing the added value of group B Streptococcus maternal immunisation in preventing maternal infection and fetal harm: population surveillance study.

ABSTRACT:

Objective

To assess the incidence of maternal group B Streptococcus (GBS) infection in England.

Design

Population surveillance augmented through data linkage.

Setting

England.

Population

All pregnant women accessing the National Health Service (NHS) in England.

Methods

Invasive GBS (iGBS) infections during pregnancy or within 6 weeks of childbirth were identified by linking Public Health England (PHE) national microbiology surveillance data for 2014 to NHS hospital admission records. Capsular serotypes of GBS were determined by reference laboratory typing of clinical isolates from women aged 15-44 years. Post-caesarean section surgical site infection (SSI) caused by GBS was identified in 21 hospitals participating in PHE SSI surveillance (2009-2015).

SUBMITTER: Lamagni T 

PROVIDER: S-EPMC9291181 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature