Effects of Zymosan on Short-Chain Fatty Acid and Gas Production in in vitro Fermentation Models of the Human Intestinal Microbiota.

ABSTRACT: In this study, the effects of zymosan (HG, hydrolyzed glucan) on the structure and metabolism of fecal microbiota in Chinese healthy people was investigated by an in vitro simulated intestinal microecology fermentation model. We found that HG significantly regulated fecal microbiota composition, including the increase of Bifidobacterium, Faecalibacterium, Prevotella and the decrease of Escherichia-Shigella. Moreover, HG significantly increased the total production of short chain fatty acids (SCFAs) and gases, in which the production of Acetic acid, Propionic acid, CO₂, and H₂ significantly increased while the production of Isovaleric acid and NH₃ significantly decreased. Additionally, the supplement of HG showed certain differences in t

SUBMITTER: Pi X 

PROVIDER: S-EPMC9291218 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature