Phenotypic Heterogeneity of Fulminant COVID-19--Related Myocarditis in Adults.

ABSTRACT:

Background

Adults who have been infected with SARS-CoV-2 can develop a multisystem inflammatory syndrome (MIS-A), including fulminant myocarditis. Yet, several patients fail to meet MIS-A criteria, suggesting the existence of distinct phenotypes in fulminant COVID-19-related myocarditis.

Objectives

This study sought to compare the characteristics and clinical outcome between patients with fulminant COVID-19-related myocarditis fulfilling MIS-A criteria (MIS-A⁺) or not (MIS-A^-).

Methods

A monocentric retrospective analysis of consecutive fulminant COVID-19-related myocarditis in a 26-bed intensive care unit (ICU).

Results

Between March 2020 and June 2021, 38 patients required ICU admission (male 66%; mean age 32 ± 15 years) for suspected fu

SUBMITTER: Barhoum P 

PROVIDER: S-EPMC9291241 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature