Impact of post-hepatectomy liver failure on morbidity and short- and long-term survival after major hepatectomy.

ABSTRACT:

Background

Post-hepatectomy liver failure (PHLF) is one of the most serious postoperative complications after hepatectomy. The aim of this study was to assess the impact of the International Study Group of Liver Surgery (ISGLS) definition of PHLF on morbidity and short- and long-term survival after major hepatectomy.

Methods

This was a retrospective review of all patients who underwent major hepatectomy (three or more liver segments) for various liver tumours between 2010 and 2018 at two Swedish tertiary centres for hepatopancreatobiliary surgery. Descriptive statistics, regression models, and survival analyses were used.

Results

A total of 799 patients underwent major hepatectomy, of which 218 patients (27 per cent) developed ISGLS-defined PHLF, including 115 patient

SUBMITTER: Baumgartner R 

PROVIDER: S-EPMC9291378 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature