Clinical implications of left atrial reverse remodelling after cardiac resynchronization therapy.

ABSTRACT:

Aims

Left atrial (LA) function is a marker of prognosis in patients with heart failure. The prognostic implications of an improvement in LA function in addition to an improvement in left ventricular (LV) function after cardiac resynchronization therapy (CRT) implantation are unknown. This study aimed to evaluate the prognostic value of a significant change in LA reservoir strain (RS) and/or LV global longitudinal strain (GLS) after initiation of CRT.

Methods and results

LARS and LVGLS were measured with speckle-tracking echocardiography. Significant improvement in LARS and LVGLS was defined as a percentage change of +5% and +20% at 6 months after CRT implantation, respectively. Patients were divided into three groups: no significant reverse remodelling (no improvement in LAR

SUBMITTER: Stassen J 

PROVIDER: S-EPMC9291382 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature